Friday, 5 October 2012
Prevention of rickets and vitamin D deficiency in infants, children, and adolescents
Guideline Objective
To provide recommendations for the prevention of rickets and vitamin D deficiency in infants, children, and adolescents
Target Popul
ation
Infants, children, and adolescents
Major Recommendations
To prevent rickets and vitamin D deficiency in healthy infants, children, and adolescents, a
vitamin D intake of at least 400 IU/day is recommended. To meet this intake requirement,
American Academy of Pediatrics (AAP) makes the following suggestions: Breastfed and partially breastfed infants should
be supplemented with 400 IU/day of vitamin D beginning in the first few days of life.
Supplementation should be continued unless the
infant is weaned to at least 1 L/day or 1 qt/day of vitamin D–fortified formula or whole milk. Whole milk should not be used until after 12 months of age. In those children between 12 months and 2 years of age for whom overweight or obesity is a concern or who have a family history of obesity, dyslipidemia, or cardiovascular disease, the use of reduced-fat milk would be appropriate (Daniels & Greer, 2008). All nonbreastfed infants, as well as older children who are ingesting < 1000 mL/day of vitamin D-fortified formula or milk, should receive a vitamin
D supplement of 400 IU/day. Other dietary sources of vitamin D, such as fortified foods, may
be included in the daily intake of each child. Adolescents who do not obtain 400 IU of vitamin D per day through vitamin D–fortified milk (100 IU per 8-oz serving) and vitamin D–fortified foods (such as fortified cereals and eggs[yolks]) should receive a vitamin D supplement of 400 IU/day. On the basis of the available evidence, serum 25-hydroxyvitamin D (25-OH-D) concentrations in infants and children should be > 50 nmol/L (20 ng/mL).
Children with increased risk of vitamin D deficiency, such as those with chronic fat malabsorption and those chronically taking antiseizure medications, may continue to be
vitamin D deficient despite an intake of 400 IU/day. Higher doses of vitamin D supplementation may be necessary to achieve normal vitamin D status in these children, and this status should be
determined with laboratory tests (e.g., for serum 25-OH-D and parathyroid hormone (PTH) concentrations and measures of bone-mineral status). If a vitamin D supplement is prescribed, 25-OH-D levels should be repeated at 3-month intervals until normal levels have been achieved.
PTH and bone-mineral status should be monitored every 6 months until they have
normalized.
Pediatricians and other health care professionals should strive to make vitamin D supplements
readily available to all children within their community,especially for those children most at risk.
Infants, children, and adolescents
Major Recommendations
To prevent rickets and vitamin D deficiency in healthy infants, children, and adolescents, a
vitamin D intake of at least 400 IU/day is recommended. To meet this intake requirement,
American Academy of Pediatrics (AAP) makes the following suggestions: Breastfed and partially breastfed infants should
be supplemented with 400 IU/day of vitamin D beginning in the first few days of life.
Supplementation should be continued unless the
infant is weaned to at least 1 L/day or 1 qt/day of vitamin D–fortified formula or whole milk. Whole milk should not be used until after 12 months of age. In those children between 12 months and 2 years of age for whom overweight or obesity is a concern or who have a family history of obesity, dyslipidemia, or cardiovascular disease, the use of reduced-fat milk would be appropriate (Daniels & Greer, 2008). All nonbreastfed infants, as well as older children who are ingesting < 1000 mL/day of vitamin D-fortified formula or milk, should receive a vitamin
D supplement of 400 IU/day. Other dietary sources of vitamin D, such as fortified foods, may
be included in the daily intake of each child. Adolescents who do not obtain 400 IU of vitamin D per day through vitamin D–fortified milk (100 IU per 8-oz serving) and vitamin D–fortified foods (such as fortified cereals and eggs[yolks]) should receive a vitamin D supplement of 400 IU/day. On the basis of the available evidence, serum 25-hydroxyvitamin D (25-OH-D) concentrations in infants and children should be > 50 nmol/L (20 ng/mL).
Children with increased risk of vitamin D deficiency, such as those with chronic fat malabsorption and those chronically taking antiseizure medications, may continue to be
vitamin D deficient despite an intake of 400 IU/day. Higher doses of vitamin D supplementation may be necessary to achieve normal vitamin D status in these children, and this status should be
determined with laboratory tests (e.g., for serum 25-OH-D and parathyroid hormone (PTH) concentrations and measures of bone-mineral status). If a vitamin D supplement is prescribed, 25-OH-D levels should be repeated at 3-month intervals until normal levels have been achieved.
PTH and bone-mineral status should be monitored every 6 months until they have
normalized.
Pediatricians and other health care professionals should strive to make vitamin D supplements
readily available to all children within their community,especially for those children most at risk.
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